Glossary Terms

The proportion of a peptide sample that consists of the intended compound, as measured by high-performance liquid chromatography (HPLC). A […]

The continuous temperature-controlled supply chain required to maintain peptide stability from manufacture through storage to use. Most reconstituted peptides require

The practice of systematically varying injection locations to prevent localized tissue damage. Repeated subcutaneous injections at the same site can

The quantity of sterile diluent (typically bacteriostatic water) added to a vial of lyophilized peptide to create an injectable solution.

The median effective dose—the dose of a compound that produces the desired therapeutic effect in 50% of the population tested.

An initial dose larger than the regular maintenance dose, administered to rapidly achieve therapeutic blood concentrations. Without a loading dose,

The condition reached when the rate of drug administration equals the rate of drug elimination, producing consistent blood concentrations over

A pharmacokinetic parameter (abbreviated Vd) that describes how extensively a drug distributes from the bloodstream into body tissues. It is

An increase in the number of receptors on a cell surface or in their sensitivity to ligands. This is the

A rapid decrease in the response to a drug after repeated administration. Unlike gradual tolerance (which develops over weeks), tachyphylaxis