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Glossary Terms

Cardiolipin

A phospholipid found exclusively in the inner mitochondrial membrane, where it constitutes approximately 20% of the total lipid content. Cardiolipin’s […]

Reactive oxygen species

Chemically reactive molecules derived from molecular oxygen, including superoxide (O₂⁻), hydrogen peroxide (H₂O₂), and hydroxyl radicals (·OH). ROS are natural

Oxidative stress

A condition in which the production of reactive oxygen species (ROS) and other oxidizing molecules exceeds the body’s antioxidant defense

Telomere

Repetitive DNA sequences (TTAGGG in humans) capping the ends of chromosomes, protecting them from degradation and fusion during cell division.

Autophagy

A cellular housekeeping process in which cells digest and recycle their own damaged or unnecessary components—organelles, misfolded proteins, and other

Observational study

A research design in which investigators observe and record outcomes without assigning treatments or interventions. Participants are not randomized; the

Publication bias

The systematic tendency for studies with positive, statistically significant results to be published more readily than studies with negative, null,

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