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Glossary Terms

metastasis

The spread of cancer from its original site to distant organs—the primary reason cancer becomes life-threatening.Metastasis is the multistep process

RGD motif

A three-amino-acid sequence (Arg-Gly-Asp) that acts as a universal ‘docking code’ recognized by integrins on cell surfaces.The RGD (arginine-glycine-aspartate) tripeptide

biofilm

A slimy, protective community of bacteria that sticks to surfaces—much harder to kill with antibiotics than free-floating bacteria.Biofilms are structured

case series

A report describing outcomes in a small group of patients—useful for generating hypotheses but too weak to prove a treatment

VPAC1/VPAC2

The two receptors that VIP binds to—found throughout the body, they mediate VIP’s effects on blood flow, inflammation, and gut

mTOR

A master switch inside cells that controls growth and metabolism—when nutrients are abundant it says ‘grow,’ when they’re scarce it

Paneth cell

A specialized cell at the base of intestinal crypts that secretes antimicrobial peptides—your gut’s built-in defense system.Paneth cells are secretory

macular edema

Swelling in the central part of the retina—the area responsible for sharp, detailed vision—usually caused by leaky blood vessels.Macular edema

acromegaly

A condition caused by too much growth hormone in adults—leading to enlarged hands, feet, and facial features.Acromegaly results from chronic

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