Evidence Tiers:Approved DrugClinical TrialsPilot / Human DataPreclinical OnlyIt's Complicated

A (24 compounds)

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Abaloparatide: What the Research Actually Shows (forthcoming)
ACTH: Melanocortin Hormone for Infantile Spasms & Nephrotic Syndrome (forthcoming)
Afamelanotide: MC1R Agonist for Erythropoietic Protoporphyria (forthcoming)
Alpha-Defensins: What the Research Actually Shows (forthcoming)
Alpha-MSH (Alpha-Melanocyte-Stimulating Hormone) (forthcoming)
Anti-VEGF Peptide Fragments for Retinal Neovascularization (forthcoming)
AOD-9604: The Growth Hormone Fragment That Failed Its Only Clinical TrialWeight Loss & Metabolic, Performance & Body Composition
Argireline vs Matrixyl: Neuromuscular Relaxation vs Collagen Stimulation (forthcoming)
Argireline vs Matrixyl: Neuromuscular Relaxation vs Collagen Stimulation (forthcoming)
Calcitonin: The Bone-Resorption-Inhibiting Peptide Hormone with Analgesic Effects (forthcoming)
Cholecystokinin (CCK): What the Research Actually Shows (forthcoming)
Ghrelin: What the Research Actually Shows (forthcoming)
Larazotide: What the Research Actually Shows (forthcoming)
Neuropeptide Y (NPY) (forthcoming)
Secretin: What the Research Actually Shows (forthcoming)
Teriparatide (Forteo): Recombinant PTH(1-34) for Anabolic Bone Formation in Severe Osteoporosis (forthcoming)

B (6 compounds)

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Beta-Defensins (forthcoming)
Bivalirudin: What the Research Actually Shows (forthcoming)
BPC-157 vs TB-500: The Evidence Behind the Wolverine Stack (forthcoming)
BPC-157 vs TB-500: The Evidence Behind the Wolverine Stack (forthcoming)

C (13 compounds)

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CagriSema: What the Research ShowsWeight Loss & Metabolic
Cartalax: The Khavinson Tripeptide for Cartilage and Joint Tissue Homeostasis (forthcoming)
Cenegermin: Recombinant NGF for Neurotrophic Keratitis (forthcoming)
CGRP (Calcitonin Gene-Related Peptide) (forthcoming)
Cilengitide (EMD121974, cyclo-RGDfV): Integrin Antagonist Anti-Angiogenic Therapy and Phase 3 Trial Failures (forthcoming)
CJC-1295 (No DAC): What the Research ShowsGrowth Hormone Secretagogues
CJC-1295 with DAC: What the Research ShowsGrowth Hormone Secretagogues
Copper Peptides for Hair: GHK-Cu vs AHK-CuInjury Recovery & Tissue Repair, Skin & Cosmetic, Hair & Follicle
Corticotropin-Releasing Hormone (CRH) (forthcoming)
Cortistatin: The Sleep-Promoting Neuropeptide with Dual Receptor Selectivity (forthcoming)
Cosyntropin: What the Research Actually Shows (forthcoming)

D (3 compounds)

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Desmopressin (DDAVP) (forthcoming)
DSIP: Delta Sleep-Inducing Peptide Research and EvidenceLongevity & Anti-Aging, Sleep, Stress & Recovery

E (4 compounds)

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Epitalon vs SS-31 (Elamipretide): Two Theories of Aging, Two Peptides (forthcoming)
Epitalon vs SS-31 (Elamipretide): Two Theories of Aging, Two Peptides (forthcoming)
Eptifibatide: What the Research Actually Shows (forthcoming)

G (7 compounds)

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Galanin (forthcoming)
GHK-Cu vs Acetyl Tetrapeptide-3: Two Peptide Approaches to Hair Loss (forthcoming)
GHK-Cu vs Acetyl Tetrapeptide-3: Two Peptide Approaches to Hair Loss (forthcoming)
GHK-Cu: What the Research Says about the Copper PeptideInjury Recovery & Tissue Repair, Hair & Follicle
GHRP-2: What the Research ShowsGrowth Hormone Secretagogues
GHRP-6: What the Research ShowsGrowth Hormone Secretagogues

I (9 compounds)

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IGF-1 DES: The Truncated High-Potency IGF-1 VariantWADAPerformance & Body Composition
IGF-1 LR3 vs IGF-1 DES: Two Modified Growth Factors, Same Parent Peptide (forthcoming)
IGF-1 LR3 vs IGF-1 DES: Two Modified Growth Factors, Same Parent Peptide (forthcoming)
IGF-1 LR3: The Extended Half-Life IGF-1 AnalogWADAPerformance & Body Composition
Intravitreal Somatostatin Analogs for Retinal Disease (forthcoming)
Ipamorelin vs Sermorelin: Two Paths to Growth Hormone Release (forthcoming)
Ipamorelin vs Sermorelin: Two Paths to Growth Hormone Release (forthcoming)

L (6 compounds)

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Lanreotide: Long-Acting Somatostatin Analog for Neuroendocrine Tumors and Acromegaly (forthcoming)
Leuprolide: What the Research Actually ShowsSexual Health & Hormonal, Cancer & Oncology
LL-37 (Cathelicidin): What the Research ShowsInjury Recovery & Tissue Repair
Lutathera (Lutetium Lu-177 Dotatate): Targeted Radionuclide Therapy for Neuroendocrine Tumors (forthcoming)

M (11 compounds)

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Magainins: Frog-Derived Amphipathic Antimicrobial Peptides (forthcoming)
MCH: What the Research Actually Shows (forthcoming)
Melanotan I (Afamelanotide) (forthcoming)
Melanotan II: What the Research Actually ShowsSexual Health & Hormonal, Tanning & Melanocortin
Melflufen (Pepaxto): Peptide-Drug Conjugate FDA Approval and Voluntary Withdrawal (forthcoming)
MK-677 (Ibutamoren): What the Research ShowsWADAGrowth Hormone Secretagogues
Motixafortide (BL-8040, BKT140): CXCR4 Antagonist for Stem Cell Mobilization and Cancer Immunotherapy (forthcoming)
MOTS-c: The Mitochondrial Peptide That Tells Your Cells to BurnLongevity & Anti-Aging, Performance & Body Composition

N (4 compounds)

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Nerve Growth Factor in Ocular Biology and Retinal Neuroprotection (forthcoming)
Nesiritide (forthcoming)
Nisin: The Ancient Antimicrobial Peptide From Lactococcus lactis (forthcoming)

O (3 compounds)

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Octreotide: Synthetic Somatostatin Analog for Neuroendocrine Tumors and Acromegaly (forthcoming)
Orexin (Hypocretin) (forthcoming)

P (14 compounds)

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PACAP (Pituitary Adenylate Cyclase-Activating Peptide) (forthcoming)
Palopegteriparatide: First PEGylated PTH(1-34) Replacement for Chronic Hypoparathyroidism (forthcoming)
Pexiganan: What the Research Actually Shows (forthcoming)
PL-8177 (Selective MC1R Agonist) (forthcoming)
PL-8177: Selective MC1R Agonist for Non-Infectious Uveitis (forthcoming)
PT-141 vs Melanotan II: FDA-Approved Metabolite vs Unapproved Parent Compound (forthcoming)
PT-141 vs Melanotan II: FDA-Approved Metabolite vs Unapproved Parent Compound (forthcoming)

R (3 compounds)

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Relaxin: What the Research Actually Shows (forthcoming)
RGN-259: Thymosin Beta-4 for Neurotrophic Keratitis & Dry Eye (forthcoming)

S (13 compounds)

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Selank vs Semax: Anxiolytic vs Nootropic from the Same Laboratory (forthcoming)
Selank vs Semax: Anxiolytic vs Nootropic from the Same Laboratory (forthcoming)
Sermorelin: What the Research ShowsGrowth Hormone Secretagogues
Setmelanotide: First-in-Class MC4R Agonist for Genetic Obesity (forthcoming)
SP+IGF-1 Ocular: Synergistic Peptide Therapy for Corneal Healing (forthcoming)

T (13 compounds)

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Temporins: Antimicrobial Peptides from the European Red Frog (forthcoming)
Thymosin Alpha-1 vs LL-37: Approved Drug vs Preclinical Antimicrobial (forthcoming)
Thymosin Alpha-1 vs LL-37: Approved Drug vs Preclinical Antimicrobial (forthcoming)
Thymosin Beta-4: What the Research ShowsWADAInjury Recovery & Tissue Repair, Hair & Follicle
Tirzepatide vs Retatrutide: Dual Agonist Meets Triple Agonist (forthcoming)
Tirzepatide vs Retatrutide: Dual Agonist Meets Triple Agonist (forthcoming)

V (1 compound)

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