Also known as: Pentapeptide-18

Stabilized enkephalin analog (Tyr-D-Ala-Gly-Phe-Leu) targeting opioid receptors on motor nerve terminals to reduce NMJ excitability. Mechanistically independent from and non-competing with argireline. No standalone clinical evidence — all human data from argireline combination study only.

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Evidence Tier: Tier 4 — Preclinical Only · Peptidings Verdict: Thin Ice